Package: simtrial
Type: Package
Title: Clinical Trial Simulation
Version: 1.0.2
Authors@R: c(
    person("Keaven", "Anderson", email = "keaven_anderson@merck.com", role = c("aut")),
    person("Yujie", "Zhao", email = "yujie.zhao@merck.com", role =  c("aut","cre")),
    person("John", "Blischak", role = c("aut")),
    person("Nan", "Xiao", role = c("ctb")),
    person("Yilong", "Zhang", role =  c("aut")),
    person("Jianxiao", "Yang", role = c("ctb")),
    person("Lili", "Ling", role = c("ctb")),
    person("Xintong", "Li", role = c("ctb")),
    person("Ruixue", "Wang", role = c("ctb")),
    person("Yi", "Cui", role = c("ctb")),
    person("Ping", "Yang", role = c("ctb")),
    person("Yalin", "Zhu", role = c("ctb")),
    person("Heng", "Zhou", role = c("ctb")),
    person("Amin", "Shirazi", role = c("ctb")),
    person("Cole", "Manschot", role = c("ctb")),
    person("Larry", "Leon", role = c("ctb")),
    person("Merck & Co., Inc., Rahway, NJ, USA and its affiliates", role = "cph",
           comment = c(ROR = "02891sr49"))
    )
Description: Provides some basic routines for simulating a clinical
        trial. The primary intent is to provide some tools to generate
        trial simulations for trials with time to event outcomes.
        Piecewise exponential failure rates and piecewise constant
        enrollment rates are the underlying mechanism used to simulate
        a broad range of scenarios such as those presented in Lin et
        al. (2020) <doi:10.1080/19466315.2019.1697738>. However, the
        basic generation of data is done using pipes to allow maximum
        flexibility for users to meet different needs.
License: GPL-3
URL: https://merck.github.io/simtrial/,
        https://github.com/Merck/simtrial
BugReports: https://github.com/Merck/simtrial/issues
Encoding: UTF-8
LazyData: true
VignetteBuilder: knitr
Depends: R (>= 4.1.0)
Imports: Rcpp, data.table (>= 1.12.4), doFuture, foreach, future,
        methods, mvtnorm, stats, survival, utils
Suggests: Matrix, covr, dplyr, ggplot2, gsDesign, gsDesign2 (>= 1.1.4),
        gt, knitr, rmarkdown, survMisc, survRM2, testthat (>= 3.0.0),
        tibble, tidyr
LinkingTo: Rcpp
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.3
Config/testthat/edition: 3
Repository: https://merck.r-universe.dev
Date/Publication: 2026-07-01 16:22:25 UTC
RemoteUrl: https://github.com/merck/simtrial
RemoteRef: HEAD
RemoteSha: f36085482ed0334e92b5110da41d3e16142cf8ae
NeedsCompilation: yes
Packaged: 2026-07-01 18:08:47 UTC; root
Author: Keaven Anderson [aut],
  Yujie Zhao [aut, cre],
  John Blischak [aut],
  Nan Xiao [ctb],
  Yilong Zhang [aut],
  Jianxiao Yang [ctb],
  Lili Ling [ctb],
  Xintong Li [ctb],
  Ruixue Wang [ctb],
  Yi Cui [ctb],
  Ping Yang [ctb],
  Yalin Zhu [ctb],
  Heng Zhou [ctb],
  Amin Shirazi [ctb],
  Cole Manschot [ctb],
  Larry Leon [ctb],
  Merck & Co., Inc., Rahway, NJ, USA and its affiliates [cph] (ROR:
    <https://ror.org/02891sr49>)
Maintainer: Yujie Zhao <yujie.zhao@merck.com>